(S)-7-fluoro-6-(4-methylpiperazin-1-yl) -10-oxo-4-thia-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid
CAS number: 100986-85-4
Groups: All Chemicals
Information:
http://en.wikipedia.org/wiki/Levofloxacin
IUPAC Name: (S)-7-fluoro-6-(4-methylpiperazin-1-yl) -10-oxo-4-thia-1-azatricyclo[7.3.1.05,13] trideca-5(13),6,8,11-tetraene-11-carboxylic acid
CAS Number: 100986-85-4
Chemical Formula: C18H20FN3O4
Synonyms: 100986-85-4, 100986-86-5, 138199-71-0 (HEMIHYDRATE), 28266_FLUKA, (3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7
H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid, 7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 2,3-dihydro-9-f
luoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, hemihydrate, (S)-, 7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 2,3-dihydro-9-f
luoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (S)-, 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-di
hydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (3S)-, (−)-Ofloxacin, AIDS002307, AIDS-002307, Ambap1065, BSPBio_002689, C07660, C18H20FN3O4, C18H20FN3O4.H2O, CCRIS 4073, CCRIS 4074, CPD000466387, Cravit, DB01137, d-Levofloxacin, DR 3354, DR3355, DR-3355, DR-3355: L-isomer of ofloxacin, DRG-0129, Elequine, Floxacin, HR 355, HR-355, Iquix, KBio2_002199, KBio2_004767, KBio2_007335, KBio3_001909, KBioGR_001605, KBioSS_002199, KS-1077, Levaquin, LEVAQUIN IN DEXTROSE 5% IN PLASTIC CONTAINER, LEVOFLOXACIN, Levofloxacine [INN-French], Levofloxacino [INN-Spanish], Levofloxacin tablet, suspension or intravenous, Levofloxacinum [INN-Latin], Levofloxacin [USAN:INN:JAN], L-Ofloxacin, LS-133260, LS-171761, LVX, MLS000759524, MLS001165709, MLS001423977, MP-376, NCGC00178529-01, (-)-Ofloxacin, Ofloxacin S-(-)-form, Oftaquix, Quixin, (R)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H
-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, (R)-isomer, R-Ofloxacin, RWJ-25213, RWJ 25213-097, (-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-ox
o-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, (S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H
-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, (-)-(S)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-ox
o-7Hpyrido[1,2,3-de]-1,4 benzoxazine-6-carboxylic acid hemihydrate, (-)-(S)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-ox
o-7Hpyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid hemihydrate, (-)-(S)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-ox
o-7H-pyridol[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid hemihydrate, SAM001246758, SMR000466387, (S)-Ofloxacin, (S)-(-)-Ofloxacin, S-(-)-Ofloxacin, SPBio_001891, Spectrum_001719, SPECTRUM1504260, Spectrum2_001676, Spectrum3_000995, Spectrum4_001123, Spectrum5_001438, Tavanic
Product Info: Fluoroquinolones belong to a group of synthetic antibiotics that are derived from basic structure of nalidixic acid and have substituents at N-1, C-5, C-7, position 8 and a fluorine atom at position 6. There are also polycyclic derivatives. Quinolone antibiotics have a ketone at position 4 and a carboxylic group at position 3. Fluoroquinolones inhibit the bacterial DNA gyrase or the topoisomerase IV enzyme, resulting the inhibition of DNA replication and transcription. Fluorine at position 6 enhances gyrase inhibition and cell penetration. Piperaziny substituents provide activity against Gram-negative bacteria and pyrrolidinyl moiety is active against Gram-positive cocci. They improve water solubility needed oral application. The function substituted at position 8 IS to control anaerobe activity.
ASK FOR QUOTATIONGroups: All Chemicals
Information:
http://en.wikipedia.org/wiki/Levofloxacin
IUPAC Name: (S)-7-fluoro-6-(4-methylpiperazin-1-yl) -10-oxo-4-thia-1-azatricyclo[7.3.1.05,13] trideca-5(13),6,8,11-tetraene-11-carboxylic acid
CAS Number: 100986-85-4
Chemical Formula: C18H20FN3O4
Synonyms: 100986-85-4, 100986-86-5, 138199-71-0 (HEMIHYDRATE), 28266_FLUKA, (3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7
H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid, 7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 2,3-dihydro-9-f
luoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, hemihydrate, (S)-, 7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 2,3-dihydro-9-f
luoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (S)-, 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-di
hydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (3S)-, (−)-Ofloxacin, AIDS002307, AIDS-002307, Ambap1065, BSPBio_002689, C07660, C18H20FN3O4, C18H20FN3O4.H2O, CCRIS 4073, CCRIS 4074, CPD000466387, Cravit, DB01137, d-Levofloxacin, DR 3354, DR3355, DR-3355, DR-3355: L-isomer of ofloxacin, DRG-0129, Elequine, Floxacin, HR 355, HR-355, Iquix, KBio2_002199, KBio2_004767, KBio2_007335, KBio3_001909, KBioGR_001605, KBioSS_002199, KS-1077, Levaquin, LEVAQUIN IN DEXTROSE 5% IN PLASTIC CONTAINER, LEVOFLOXACIN, Levofloxacine [INN-French], Levofloxacino [INN-Spanish], Levofloxacin tablet, suspension or intravenous, Levofloxacinum [INN-Latin], Levofloxacin [USAN:INN:JAN], L-Ofloxacin, LS-133260, LS-171761, LVX, MLS000759524, MLS001165709, MLS001423977, MP-376, NCGC00178529-01, (-)-Ofloxacin, Ofloxacin S-(-)-form, Oftaquix, Quixin, (R)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H
-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, (R)-isomer, R-Ofloxacin, RWJ-25213, RWJ 25213-097, (-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-ox
o-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, (S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H
-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, (-)-(S)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-ox
o-7Hpyrido[1,2,3-de]-1,4 benzoxazine-6-carboxylic acid hemihydrate, (-)-(S)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-ox
o-7Hpyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid hemihydrate, (-)-(S)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-ox
o-7H-pyridol[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid hemihydrate, SAM001246758, SMR000466387, (S)-Ofloxacin, (S)-(-)-Ofloxacin, S-(-)-Ofloxacin, SPBio_001891, Spectrum_001719, SPECTRUM1504260, Spectrum2_001676, Spectrum3_000995, Spectrum4_001123, Spectrum5_001438, Tavanic
Product Info: Fluoroquinolones belong to a group of synthetic antibiotics that are derived from basic structure of nalidixic acid and have substituents at N-1, C-5, C-7, position 8 and a fluorine atom at position 6. There are also polycyclic derivatives. Quinolone antibiotics have a ketone at position 4 and a carboxylic group at position 3. Fluoroquinolones inhibit the bacterial DNA gyrase or the topoisomerase IV enzyme, resulting the inhibition of DNA replication and transcription. Fluorine at position 6 enhances gyrase inhibition and cell penetration. Piperaziny substituents provide activity against Gram-negative bacteria and pyrrolidinyl moiety is active against Gram-positive cocci. They improve water solubility needed oral application. The function substituted at position 8 IS to control anaerobe activity.
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