(-)-Bilobalide
CAS number: 33570-04-6
Groups: All Chemicals, Phytochemicals
Information:
IUPAC Name: (5aR-(3aS*,5aalpha,8beta,8aS*,9alpha,10aalpha))-9-(1,1-Dimethylethyl)-10,10a-dihydro-8,9-dihydroxy- 4H,5aH,9H-furo(2,3-b)furo(3',2':2,3)cyclopenta(1,2-c)furan-2,4,7(3H,8H)-trione;
CAS Number: 33570-04-6
Chemical Formula: C15H18O8
Synonyms: 33570-04-6, 4H,5aH,9H-Furo[2,3-b]furo[3',2':2,3]cyclopenta[1,2-c]furan-2,4,7(3H,8H
)-trione, 9-(1,1-dimethylethyl)-10,10a-dihydro-8,9-dihydroxy-,(3aS,5aR
,8R,8aS,9R,10aS)-, 4H,5aH,9H-Furo(2,3-b)furo(3',2':2,3)cyclopenta(1,2-c)furan-2,4,7(3H,8H
)-trione, 9-(1,1-dimethylethyl)-10,10a-dihydro-8,9-dihydroxy-, (5aR-(3
aS*,5aalpha,8beta,8aS*,9alpha,10aalpha))-, AIDS029698, AIDS-029698, Ambap2349, Bilobalide, CID73581, LS-183112, MLS000563448, NCGC00142501-01, NCGC00142501-02, SMR000232342, ST057155
Product info:
Ginkgo biloba extract contain specific terpenoids called ginkgolides (ginkgolide A, ginkgolide B, ginkgolide C - diterpenes) and bilobalide (pentanorditerpene). Ginkgolide A (GA) and ginkgolide B (GB) are the main molecular forms of ginkgolides. These compounds are non-competitive antagonists of the GABAA and glycine receptors, and are structurally related to picrotoxin (PTX), also a non-competitive antagonist of these receptors. These compounds are thought to bind in the channel of these receptors. The medical benefits of GINKGO BILOBA EXTRACT rely primarily on two groups of active components: the ginkgo flavone glycosides and the terpene lactones. The ginkgo flavone glycoside designation on GBE labels indicates the carefully measured balance of bioflavonoids. These bioflavonoids are primarily responsible for GBE's antioxidant activity and ability to inhibit platelet aggregation. These two actions may help GBE prevent circulatory diseases such as atherosclerosis and support the brain and central nervous system. The unique terpene lactone components found in GBE, known as ginkgolides and bilobalide typically make up 6% of the extract. They are associated with increased circulation to the brain and other parts of the body as well as exert a protective action on nerve cells. Ginkgolides may improve circulation and inhibit platelet-activating factor. Bilobalide is known to protect the cells of the nervous system.
ASK FOR QUOTATIONGroups: All Chemicals, Phytochemicals
Information:
IUPAC Name: (5aR-(3aS*,5aalpha,8beta,8aS*,9alpha,10aalpha))-9-(1,1-Dimethylethyl)-10,10a-dihydro-8,9-dihydroxy- 4H,5aH,9H-furo(2,3-b)furo(3',2':2,3)cyclopenta(1,2-c)furan-2,4,7(3H,8H)-trione;
CAS Number: 33570-04-6
Chemical Formula: C15H18O8
Synonyms: 33570-04-6, 4H,5aH,9H-Furo[2,3-b]furo[3',2':2,3]cyclopenta[1,2-c]furan-2,4,7(3H,8H
)-trione, 9-(1,1-dimethylethyl)-10,10a-dihydro-8,9-dihydroxy-,(3aS,5aR
,8R,8aS,9R,10aS)-, 4H,5aH,9H-Furo(2,3-b)furo(3',2':2,3)cyclopenta(1,2-c)furan-2,4,7(3H,8H
)-trione, 9-(1,1-dimethylethyl)-10,10a-dihydro-8,9-dihydroxy-, (5aR-(3
aS*,5aalpha,8beta,8aS*,9alpha,10aalpha))-, AIDS029698, AIDS-029698, Ambap2349, Bilobalide, CID73581, LS-183112, MLS000563448, NCGC00142501-01, NCGC00142501-02, SMR000232342, ST057155
Product info:
Ginkgo biloba extract contain specific terpenoids called ginkgolides (ginkgolide A, ginkgolide B, ginkgolide C - diterpenes) and bilobalide (pentanorditerpene). Ginkgolide A (GA) and ginkgolide B (GB) are the main molecular forms of ginkgolides. These compounds are non-competitive antagonists of the GABAA and glycine receptors, and are structurally related to picrotoxin (PTX), also a non-competitive antagonist of these receptors. These compounds are thought to bind in the channel of these receptors. The medical benefits of GINKGO BILOBA EXTRACT rely primarily on two groups of active components: the ginkgo flavone glycosides and the terpene lactones. The ginkgo flavone glycoside designation on GBE labels indicates the carefully measured balance of bioflavonoids. These bioflavonoids are primarily responsible for GBE's antioxidant activity and ability to inhibit platelet aggregation. These two actions may help GBE prevent circulatory diseases such as atherosclerosis and support the brain and central nervous system. The unique terpene lactone components found in GBE, known as ginkgolides and bilobalide typically make up 6% of the extract. They are associated with increased circulation to the brain and other parts of the body as well as exert a protective action on nerve cells. Ginkgolides may improve circulation and inhibit platelet-activating factor. Bilobalide is known to protect the cells of the nervous system.
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