product information
(2S)-4-amino-n-[(1r,2s,3s,4r,5s)-5-amino-2-[(2s,3r,4s,5s,6r)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-[(2r,3r,4s,5s,6r)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy-3-hydroxycyclohexyl]-2-hydroxybutanamide
CAS number: 37517-28-5
Groups: All Chemicals
Information:
IUPAC Name: (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy-3-hydroxycyclohexyl]-2-hydroxybutanamide

CAS Number: 38859-32-4

Chemical Formula: C22H43N5O13

Synonyms: 108914-65-4, 110660-81-6, 110660-83-8, 111319-93-8, 1-N-(L(-)-gamma-Amino-alpha-hydroxybutyryl)kanamycin A, (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-[(2S,3R,4S,5S,6R)-4-amino-3
,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-[(2R,3R,4S,5S,6R)-6-(ami
nomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy-3-hydroxycyclohexyl]-2-hydroxy
butanamide, (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-[(2S,3R,4S,5S,6R)-4-amino-3
,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-4-[(2R,3R,4S,5S
,6R)-6-(aminomethyl)-3,4,5-trihydroxy-tetrahydropyran-2-yl]oxy-3-hydro
xy-cyclohexyl]-2-hydroxy-butanamide, (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-[(2S,3R,4S,5S,6R)-4-amino-3
,5-dihydroxy-6-methylol-tetrahydropyran-2-yl]oxy-4-[(2R,3R,4S,5S,6R)-6
-(aminomethyl)-3,4,5-trihydroxy-tetrahydropyran-2-yl]oxy-3-hydroxy-cyc
lohexyl]-2-hydroxy-butyramide, (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-(3-amino-3-deoxy-alpha-D-gl
ucopyranosyloxy)-4-(6-amino-6-deoxy-alpha-D-glucopyranosyloxy)-3-hydro
xycyclohexyl]-2-hydroxybutanamide, (2S)-4-amino-N-{(1R,2S,3S,4R,5S)-5-amino-2-[(3-amino-3-deoxy-alpha-D-g
lucopyranosyl)oxy]-4-[(6-amino-6-deoxy-alpha-D-glucopyranosyl)oxy]-3-h
ydroxycyclohexyl}-2-hydroxybutanamide, (2S)-N-[(1R,2S,3S,4R,5S)-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-tri
hydroxy-oxan-2-yl]oxy-5-azanyl-2-[(2S,3R,4S,5S,6R)-4-azanyl-3,5-dihydr
oxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-hydroxy-cyclohexyl]-4-azanyl-2-hy
droxy-butanamide, 37517-28-5, 38859-32-4, 39831-55-5 (DISULFATE), AB00513828, AIDS007651, AIDS-007651, AIDS208770, AIDS-208770, Amicacin, Amiglyde-V, amikacin, Amikacina [INN-Spanish], Amikacin Base, Amikacin Dihydrate, Amikacine [INN-French], Amikacin plus Tumor Necrosis Factor, AMIKACIN SULFATE, Amikacinum [INN-Latin], Amikacin [USAN:BAN:INN], Amikacin (USP/INN), Amikavet, Amikin (Disulfate), AMK, Antibiotic BB-K 8, ANTIBIOTIC BB-K8, Arikace, BB-K8, BB-K 8, BPBio1_000671, Briclin, BSPBio_000609, C06820, C22H43N5O13, CHEBI:2637, D02543, DB00479, D-Streptamine, O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-6)-O-(6-ami
no-6-deoxy-alpha-D-glucopyranosyl-(1-4))-N1-(4-amino-2-hydroxy-1-oxobu
tyl)-2-deoxy-, (S)-, D-Streptamine, O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1->6)-O-(6-am
ino-6-deoxy-alpha-D-glucopyranosyl-(1->4))-N(sup 1)-(4-amino-2-hydroxy
-1-oxobutyl)-2-deoxy-, (S)-, D-Streptamine, O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-6)-O-(6-ami
no-6-deoxy-alpha-D-glucopyranosyl-(1-4))-N(sup 1)-(4-amino-2-hydroxy-1
-oxobutyl)-2-deoxy-, (S)-, D-Streptamine, O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-6)-O-(6-ami
no-6-deoxy-alpha-D-glucopyranosyl-(1,4))-N(sup 1)-(4-amino-2-hydroxy-1
-oxobutyl)-2-deoxy-, (S)-, EINECS 253-538-5, HSDB 3583, Kaminax, LS-146896, Lukadin, Mikavir, NCGC00093350-02, NCGC00093350-03, Novamin, NSC177001, NSC 177001, O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1->4)-O-(6-amino-6-deoxy-alp
ha-D-glucopyranosyl-(1->6))-N(3)-(4-amino-L-2-hydroxybutyryl)-2-deoxy-
L-streptamine, O-3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(6-amino-6-deoxy-alph
a-D-glucopyranosyl-(1-6))-N(sup 3)-(4-amino-L-2-hydroxybutyryl)-2-deox
y-L-streptamine, O-3-Amino-3-deoxy-.alpha.-D-glucopyranosyl-(1->6)-O-[6-amino-6-deoxy-.
alpha.-D-glucopyranosyl-(1->4)]-1-(4-amino-2-hydroxy-1-oxobutyl)-2-deo
xy-D-streptamine, Pierami, Prestwick3_000395, STK039706

Product Info: Amikacin sulfate [ chemically : D-Streptamine, O-3-amino-3-deoxy-alpha-D- glucopyranosyl- (1-6)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1-4))- N1-(4-amino-2-hydroxy-1- oxobutyl)- 2-deoxy-, (S)-sulfate (1:2) (salt)] is a semi-synthetic aminoglycoside antibiotic derived from kanamycin. Its spectrum is somewhat broader than that of other aminoglycosides, including Serratia and Acinetobacter species, as well as certain staphylococci and streptococci. It is the most effective agent against gram-negative bacilli that have some aminoglycoside resistance. It is used for the treatment of serious infections resistant to gentamicin and tobramycin (bone infections, respiratory tract infections, endocarditis, and septicemia).

Aminoglycoside is any of a group of antibiotics derived from various species of Streptomyces or Micromonosporaceae, while some of which are produced synthetically. Aminoglycosides inhibit bacterial protein synthesis by binding with the 30S ribosomal subunit and in some cases the 50S subunit, causing miscoding and thus inhibiting initiation and elongation during protein synthesis. They include;
Amikacin
Gentamicin
Kanamycin
Neomycin
Netilmicin
Paromomycin
Streptomycin
Tobramycin
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