product information
(S)-naringenin
CAS number: 480-41-1
Groups: Pharmaceutical, All Chemicals, Plant extracts (Herbal Extracts), Phytochemicals
Information:
http://en.wikipedia.org/wiki/Naringenin

IUPAC Name: 5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one

CAS Number: 67604-48-2

Chemical Formula: C15H12O5

Synonyms: ()-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one, 4;,5',7-trihydroxyflavanone, 4',5,7-Trihydroxyflavanone, 480-41-1, 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-, 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-,
(S)-, 5,7-Dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one, 67604-48-2, 71155_FLUKA, ACon1_000582, AI3-23355, BE 14348A, BE-14348A, BPBio1_000630, BSPBio_000572, C15H12O5, CCRIS 5839, CHEBI:50202, DB03467, EINECS 207-550-2, EINECS 266-769-1, Flavanone, 4',5,7-trihydroxy-, Flavanone, 4',5,7-trihydroxy- (8CI), flavanone naringenin, LS-39547, LS-5089, MEGxp0_000358, MLS000028739, MLS000738094, MLS001146907, N5893_SIGMA, NARIGENIN, naringenin, (-)-Naringenin, ()-Naringenin, ( )-Naringenin; 4?,5,7-Trihydroxyflavanone; H-1-benzopyran-4-one, naringenin-7-sulfate, NARINGENIN-CMPD, Naringenine, Naringenin (NAR), naringetol, NCGC00095963-01, NCGC00095963-02, NCGC00095963-03, NSC11855, NSC 11855, NSC34875, NSC 34875, Oprea1_194140, pelargidanon, Prestwick0_000466, Prestwick1_000466, Prestwick2_000466, Prestwick3_000466, Prestwick_531, S00279, (S)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone, (S)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-on
e, Salipurol, salipurpol, SBB006461, SMP1_000060, SMR000059039, (S)-Naringenin, SPBio_002511, T66001_ALDRICH

Product Info: Naringenin is a flavonone that is considered to have a bioactive effect on human health as antioxidant, radical scavenger, antiinflammatory, carbohydrate metabolism promoter, immunity system modulater. It works as an anti-ulcer agent and estrogen antagonist which inhibit the action or biosynthesis of estrogenic compounds. Naringin is the aglycones of naringenin. Naringin is known as an antioxidant in the body. in biology, antioxidants act to protect cells against free radicals. Free radicals play an important role in a number of biological processes such as the intracellular killing of bacteria by neutrophil granulocytes and certain cell signaling processes. However, because of their reactivity, free radicals can cause side reactions resulting in cell damage, which may contribute to the development of cardiovascular disease and cancer. Lipids, protein and nucleic acids are weak to free radicals. Free radicals may be involved in the mechanisms of aging itself also. The body has a number of mechanisms to minimize free radical induced damage and to repair damage. Antioxidant enzymes produced in the body play a key role in these defense mechanisms, such as glutathione peroxidase, glutathione reductase, catalase, thioredoxin reductase and superoxide dismutase. Additionally, chemical antioxidants neutralize free radicals by accepting or donating an electron to eliminate the unpaired condition. These antioxidants include three vitamins (vitamin A, vitamin C and vitamin E), polyphenols, bilirubin and uric acid. Synthetic or natural antioxidants are widely used in nutrition and medicine and prepared foods for the effect to slow down the natural aging process and to prevent or delay certain diseases that result from cellular damage. But there should be considerable researches whether antioxidant supplementation provide beneficial effect, and if so, which and what amount of antioxidants are optimal. There are hundreds of different types of nutritional antioxidants include vitamins, coenzymes, selenium, minerals, hormones, carotenoids, non-carotenoid terpenoids, flavonoids (flavonols, flavones isoflavones, flavanols,, anthocyanidins), nonflavonoid phenolics, polyphenolics and their esters (ellagic acids, citric acids, uric acids, gallic acids, salicylic acids, rosmarinic acids, cinnamic acids, chlorogenic acids, chicoric acids).

Flavonoid is any member of a class of widely distributed biological natural products containing aromatic heterocyclic skeleton of flavan (2-Phenylbenzopyran) but no nitrogen in plants. Generally, flavonoids are biological pigments providing colours from red to blue in flowers, fruit and leaves. Besides their coloring in plants, flavonoids have important roles in the growth and development of plants; protection against UV-B radiation; forming antifungal barriers; antimicrobial, insecticidal and oestrogenic activities; plant reproduction. Flavonoids also exhibit a wide range of biological properties including anti-microbial, insecticidal and oestrogenic activities. Flavonoids are usually classified into main 6 subgroups as below plus flavans, neoflavonoids, flavonols, aurons, catechins according to the structural patterns.

* Flavonols (Hydroxy derivatives of flavone): Fisetin, Galangin, Kaempferide, Kaempferol, Morin, Myricetin, Myricitrin, Quercetin, Quercetrin, Rhamnetin, Robinin, Rutin, Spirenoside

* Flavones (skeleton: 2-phenylchromen-4-one): Apigenin, Baicalein, Chrysin, Diosmetin, Diosmin, Flavone, Luteolin, Rpoifolin,Tangeretin, Techtochrysin, Rhamnazin, Nobiletin, Natsudaidain.

* Isoflavones (skeleton: 3-phenylchromen-4-one): Daidzin, Genistein, Irilone, Luteone, Prunetin, Pratensein,

* Flavonones (derivation by reduction of the 2(3) C=C bond): Eriodictyol, Hesperidin, Hesperetin, Likvirtin, Naringin; Naringenin; Pinocembrin

* Flavanols (derivation by reduction of the keto group):(+)-Catechin, (+)-Gallocatechin, (-)-Epicatechin (EC), (-)-Epigallocatechin (EGC), (-)-Epicatechin 3-gallate (ECG), (-)-Epigallocatechin 3-gallate (EGCG), Theaflavin, Theaflavin 3-gallate, Theaflavin 3'-gallate, Theaflavin 3,3' digallate, Thearubigins

* Anthocyanidins (aglycones of the glycoside anthocyanins): Apigeninidin, Cyanidin, Delphinidin, Diosmetinidin, Guibourtinidin, Fisetinidin, Luteolinidin, Malvidin, Pelargonidin, Peonidin, Robinetinidin, Tricetinidin, Capensinidin, Petunidin, Europinidin, Aurentinidin, Columnidin, 5-Desoxy-malvidin, 5-Desoxy-peonidin, Hirsutinidin, Rosinidin
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