product information
(+-)-4'-Cyano-alpha,alpha,alpha-trifluoro-3-((p-fluorophenyl)sulfonyl) -2-methyl-m-lactotoluidide
CAS number: 90357-06-5
Groups: Pharmaceutical, All Chemicals
Information:
IUPAC Name: N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(4-fluorophenyl)sulfonyl-2-hyd
roxy-2-methylpropanamide

CAS Number: 90357-06-5

Chemical Formula: C18H14F4N2O4S

Synonyms: 4'-cyano-3-(4-fluorophenylsulfonyl)-2-hydroxy-2-methyl-3'-(trifluorome
thyl)propionanilide, (+-)-4'-Cyano-alpha,alpha,alpha-trifluoro-3-((p-fluorophenyl)sulfonyl)
-2-methyl-m-lactotoluidide, 90357-06-5, Astra brand of bicalutamide, AstraZeneca brand of bicalutamide, bicalutamide, Bicalutamide (JAN/USP/INN), Bicalutamide [USAN:INN:BAN], BRN 5364666, C053541, C08160, C18H14F4N2O4S, Casodex, Casodex (TN), CID2375, Cosudex, CPD000466329, D00961, ICI 176334, ICI-176334, LS-119125, MLS000759437, MLS001424047, N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(4-fluorophenyl)sulfonyl-2-hyd
roxy-2-methylpropanamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(4-fluorophenyl)sulfonyl-2-hyd
roxy-2-methyl-propanamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(4-fluorophenyl)sulfonyl-2-hyd
roxy-2-methyl-propionamide, NCGC00167977-01, NSC722665, propanamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)
sulfonyl]-2-hydroxy-2-methyl-,(+-), Propanamide, N-(4-cyano-3-(trifluoromethyl)phenyl)-3-((4-fluorophenyl)
sulfonyl)-2-hydroxy-2-methyl-, (+-)-, Propanamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)
sulfonyl]-2-hydroxy-2-methyl-,, Raffolutil, SAM001246612, SMR000466329, TL8005814, Zeneca brand of bicalutamide

Product Info: Bicalutamide is capable of inhibiting the biological effects of male sex hormones (androgens). Antiandrogens are sometimes used in the treatment of prostate cancer. Bicalutamide is used for therapy of prostatic carcinoma, in combination with measures to lower testosterone levels; administered orally. Only R-enantiomer of bicalutamide is antiandrogenically active; the S-enantiomer is inactive. But commercial bicalutamide is a racemate. The chemical designation is N-[4-cyano-3-(trifluoromethyl)phenyl]- 3-(4-fluorophenyl)sulfonyl-2- hydroxy-2-methyl- propanamide. Bicalutamide is a white to off-white powder, practically insoluble in water.

Antiandrogens
Antiandrogen
CAS RN
1,6,10-Trihydroxy-2-(hydroxymethyl)-8,10-dimethyl-9(10H)-anthracenone 154163-90-3
1,6,10-Trihydroxy-2,8,10-trimethyl-9(10H)-anthracenone 154163-89-0
15-Hydroxycyproterone acetate 114884-50-3
17,17-Dimethyl-18-norandrosta-4,13-dien-3-one 1971-59-1
17beta-Hydroxy-2alpha,2beta,17alpha-trimethyl-8alpha-estra-4,9,11- trien-3-one 42438-88-0
17-Hydroxycyproterone acetate 65423-26-9
17-N,N-Diethylcarbamoyl-4-methyl-4-azaandrostane-3-one 73671-86-0
2,2,4,6,6,8-Hexamethyl-4,8-diphenylcyclotetrasiloxane 4657-20-9
2',3alpha'-Tetrahydrofuran-2'-spiro-17-(6alpha,7alpha-difluoromethylene- 1alpha,2alpha -methylene)-4-androsten-3-one 57129-44-9
2-Azachlormadinone acetate 105165-23-9
3-(Cyclohex-3-en-1-on-4-yl)-4-(4-hydroxyphenyl)hexane 129579-58-4
3-alpha-Hydroxy-cyproterone acetate 167356-55-0
3-Chloro-4-(2-amino-3-chlorophenyl)pyrrole 16386-65-5
4-(3,4,4-Trimethyl-5-oxo-2-thioxo-1-imidazolidinyl)-2-(trifluoromethyl) benzonitrile 143782-25-6
4-(4,4-Dimethyl-2,5-dioxo-3-(4-hydroxybutyl)-1-imidazolidinyl)- 2-(trifluoromethyl)benzonitrile 154992-24-2
4-(4,4-Dimethyl-3-(4-hydroxybutyl)-5-oxo-2-thioxo-1-imidazolidinyl)- 2-(trifluoromethyl)benzonitrile 155180-53-3
4,5-Secodihydrotestosterone 76760-84-4
4,6-Estradiene-3,17-dione 13209-45-5
6,7-Epoxycyproterone acetate 148749-29-5
6,7-Epoxy-cyproterone acetate 40007-74-7
6-alpha-Bromo-17-beta-hydroxy-17-alpha-methyl-4-oxa-5-alpha- androstan-3-one 24543-59-7
7-Acetyl-4,4a,4b,5,6,7,8,8a,9,10-decahydro-2(3H)-phenanthrone 2327-61-9
7alpha-(Methylthio)spironolactone S-oxide 38753-75-2
7alpha-Thiospironolactone 38753-76-3
7-Thiomethylspirolactone 38753-77-4
Anthrasteroid 1 120542-29-2
Anthrasteroid 2 120542-30-5
Benorterone 3570-10-3
Bicalutamide 90357-06-5
Cioteronel 89672-11-7
Cyoctol 105635-64-1
Cyproterone 2098-66-0
Cyproterone acetate 427-51-0
Delmadinone 15262-77-8
Delmadinone acetate 13698-49-2
Diane 60528-19-0
Dutasteride 164656-23-9
Edogestrone 809-01-8
Finasteride 98319-26-7
Flutamide 13311-84-7
Hydroxyflutamide 52806-53-8
Inocoterone acetate 83646-86-0
Ketoconazole 65277-42-1
Liarozole 115575-11-6
Methyl 3-oxo-4-methyl-4-aza-5alpha-androst-1-ene-17beta-carboxylate 103335-44-0
Mifentidine 83184-43-4
N-(2-Chloromethyl-2-hydroxypropionyl)-3,4,5-trichloroaniline 65372-80-7
N-(3,5-Dimethyl-4-isoxazolylmethyl)phthalimide 39962-28-2
Nilutamide 63612-50-0
Nordinone 33122-60-0
Osaterone acetate ester 105149-00-6
Oxendolone 33765-68-3
Oxyma 57361-81-6
Pleconaril 153168-05-9
Spironolactone 52-01-7
Topterone 60607-35-4
Vinclozolin 50471-44-8
Zanoterone 107000-34-0
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